Hemophilia
Hemophilia is a blood disorder in which blood does not clot properly.
Bleeding disorders can be due to blood vessels defect, the coagulation or the blood platelets. A patient having Hemophilia may bleed continuously for an extended time than a healthy person after a surgery or an injury.
The blood coagulation is a process that changes the blood from liquid state to the solid state and it involves many clotting factors. This mechanism produces fibrin which combines with the platelet to stop the bleeding.
When coagulation mechanism is not effective, the blood does not clot and the bleeding continues.
Patients with Hemophilia A or B have genetic defects in them that prevents the blood clotting factors.
Types of hemophilia
Hemophilia A or B
Hemophilia A is due to the deficiency of factor VIII and Hemophilia B is caused due to the deficiency of factor IX.
Both the types are almost same as they are associated with the bleeding in the joints, muscles and internal or external bleeding after an injury or a surgery.
If the bleeding occurs repeatedly, it permanently damages the joints and muscles like ankles, knees and elbows.
Approximately 1 in 5,000 males born with Hemophilia A, 1 in 30,000 males born with Hemophilia B.
This disease can affect people of all races and ethnic origins. The conditions are X- linked so most of the sufferers are male. Female carriers may also bleed abnormally.
People with Hemophilia have a genetic change in the affected gene on X chromosome, as a result production of VIII and IX creates a bleeding capacity.
About one third of Hemophilia patients have no family history of the disease.
Development of Hemophilia
The patients develop the Hemophilia in their lifetime and mostly do not have a genetic cause. It is developed when a body forms antibodies that attack the blood clotting factors. In this way blood clotting system is affected. Patients oh Hemophilia can be male or female. This disease is associated with old age and it can complicate the pregnancy.
Read more
Hemophilia is a blood disorder in which blood does not clot properly.
Bleeding disorders can be due to blood vessels defect, the coagulation or the blood platelets. A patient having Hemophilia may bleed continuously for an extended time than a healthy person after a surgery or an injury.
The blood coagulation is a process that changes the blood from liquid state to the solid state and it involves many clotting factors. This mechanism produces fibrin which combines with the platelet to stop the bleeding.
When coagulation mechanism is not effective, the blood does not clot and the bleeding continues.
Patients with Hemophilia A or B have genetic defects in them that prevents the blood clotting factors.
Types of hemophilia
Hemophilia A or B
Hemophilia A is due to the deficiency of factor VIII and Hemophilia B is caused due to the deficiency of factor IX.
Both the types are almost same as they are associated with the bleeding in the joints, muscles and internal or external bleeding after an injury or a surgery.
If the bleeding occurs repeatedly, it permanently damages the joints and muscles like ankles, knees and elbows.
Approximately 1 in 5,000 males born with Hemophilia A, 1 in 30,000 males born with Hemophilia B.
This disease can affect people of all races and ethnic origins. The conditions are X- linked so most of the sufferers are male. Female carriers may also bleed abnormally.
People with Hemophilia have a genetic change in the affected gene on X chromosome, as a result production of VIII and IX creates a bleeding capacity.
About one third of Hemophilia patients have no family history of the disease.
Development of Hemophilia
The patients develop the Hemophilia in their lifetime and mostly do not have a genetic cause. It is developed when a body forms antibodies that attack the blood clotting factors. In this way blood clotting system is affected. Patients oh Hemophilia can be male or female. This disease is associated with old age and it can complicate the pregnancy.
Read more

